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Proteins & Enzymes
140 recordsp53 · Cellular tumor antigen p53
A 393-amino-acid transcription factor that helps determine how a stressed cell responds to damage.
2-Oxoglutarate dehydrogenase complex · EC 1.2.4.2
Oxidatively decarboxylates 2-oxoglutarate to succinyl-CoA.
3-Hydroxy-3-methylglutaryl-CoA lyase · EC 4.1.3.4
Produces acetoacetate and acetyl-CoA from HMG-CoA in leucine catabolism.
3-Methylcrotonyl-CoA carboxylase · EC 6.4.1.4
Biotin-dependent enzyme in leucine catabolism.
4E-BP1 (EIF4EBP1) · eukaryotic translation initiation factor 4E binding protein 1
A translation-regulating protein. mTORC1-dependent phosphorylation can reduce 4E-BP1 binding to eIF4E, helping control translation initiation.
6-Phosphogluconate dehydrogenase · EC 1.1.1.44
Oxidatively decarboxylates 6-phosphogluconate to ribulose 5-phosphate and NADPH.
6-Phosphogluconolactonase · EC 3.1.1.31
Hydrolyzes 6-phosphogluconolactone to 6-phosphogluconate.
Acetyl-CoA acyltransferase 2 · EC 2.3.1.16
Cleaves 3-ketoacyl-CoA with CoA, releasing acetyl-CoA and a shortened acyl-CoA.
Acetyl-CoA carboxylase · EC 6.4.1.2
Biotin-dependent enzyme that makes malonyl-CoA, the committed precursor for fatty-acid synthesis.
Aconitase 2 · EC 4.2.1.3
Reversibly isomerizes citrate to isocitrate through cis-aconitate.