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HomeMetabolismGlyceraldehyde-3-phosphate dehydrogenase
Protein · enzymePROTEIN · ENZYME RECORD

Glyceraldehyde-3-phosphate dehydrogenase

Oxidizes G3P with NAD+ and adds inorganic phosphate through a catalytic-cysteine thioester intermediate.

GlycolysisHomo sapiens
REFERENCE IDENTIFIER1.2.1.12EC record
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Glyceraldehyde-3-phosphate dehydrogenase is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Oxidizes G3P with NAD+ and adds inorganic phosphate through a catalytic-cysteine thioester intermediate.
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HUMAN GENESGAPDHExplore gene
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Catalyzes a step inGlycolysisUsesGlyceraldehyde 3-phosphateUsesNAD+UsesInorganic phosphateProduces1,3-BisphosphoglycerateProducesNADHProducesProtonEncoded byGAPDH
STRUCTURED REACTIONS

Reactions it catalyzes

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Oxidation of glyceraldehyde 3-phosphate

G3P is oxidized. NAD+ picks up electrons to become NADH, and a phosphate is added to form a high-energy acyl-phosphate.

Glycolysis · reversible