EGFR–HER2 Heterodimer
EGFR–ERBB2 receptor tyrosine kinase heterodimer
A representative ERBB receptor pair. Ligand-bound EGFR can pair with HER2; HER2 has no established soluble ligand of its own and can feed both MAPK and PI3K signaling through receptor-associated complexes.
Overview
EXPLORE BY LEVELEGFR–HER2 Heterodimer is a team of proteins that works together as one signaling unit. A representative ERBB A protein that detects a signal, such as a hormone, and helps a cell respond. pair. Ligand-bound EGFR can pair with HER2; HER2 has no established soluble ligand of its own and can feed both MAPK and PI3K signaling through A protein that detects a signal, such as a hormone, and helps a cell respond.-associated complexes.
Quick Facts
AT A GLANCEFollow the Connections
See how EGFR–HER2 Heterodimer links to other biological records.
All 4 Structured Connections
Recommended Reading
Trusted references for learning more about EGFR–HER2 Heterodimer.
Research Claims
A representative ERBB receptor pair. Ligand-bound EGFR can pair with HER2; HER2 has no established soluble ligand of its own and can feed both MAPK and PI3K signaling through receptor-associated complexes.