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MoleculeMETABOLITE RECORD

Magnesium ion

A metal cofactor for the kinases and for enolase. Kinases use ATP and ADP as Mg2+ complexes.

GlycolysisHomo sapiens
REFERENCE IDENTIFIERCHEBI:18420ChEBI record
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Learn about Magnesium ion

Magnesium ion is a small molecule that cells make, use, or change in connected metabolic reactions.

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Record type: molecule. A metal cofactor for the kinases and for enolase. Kinases use ATP and ADP as Mg2+ complexes.
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Connected records

6 links
Cofactor inGlycolysisHandled byHexokinaseHandled byPhosphofructokinase-1Handled byPhosphoglycerate kinaseHandled byEnolaseHandled byPyruvate kinase
STRUCTURED REACTIONS

Where it appears

Open metabolism map
1

Phosphorylation of glucose

One ATP is spent to add a phosphate to glucose. The charged phosphate traps glucose inside the cell.

Glycolysis · irreversible
3

Phosphorylation of fructose 6-phosphate

A second ATP adds a phosphate to carbon 1. This commits the sugar to glycolysis and is the pathway's main control point.

Glycolysis · irreversible
7

First ATP-generating step

1,3-Bisphosphoglycerate gives a phosphate to ADP and makes ATP. Across both three-carbon halves, this repays the two ATP invested.

Glycolysis · reversible
9

Dehydration to phosphoenolpyruvate

Removing a water molecule forms phosphoenolpyruvate, whose phosphate has very high transfer potential.

Glycolysis · reversible
10

Second ATP-generating step

PEP gives its phosphate to ADP, forming ATP and pyruvate. This second ATP-making step is where glycolysis turns a net profit.

Glycolysis · irreversible