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Protein

GRB2

growth factor receptor bound protein 2

An adaptor protein that helps recruit SOS-family exchange factors to activated receptor signaling complexes.

Overview

EXPLORE BY LEVEL

GRB2 is a protein that helps pass or control signals inside cells. An adaptor protein that helps recruit SOS-family exchange factors to activated signaling complexes.

Quick Facts

AT A GLANCE
Encoded byGRB2
Rolereceptor tyrosine kinase; mapk signaling

Follow the Connections

See how GRB2 links to other biological records.

Open network
GeneGRB2encodesPathwayReceptor Tyrosine kinase signalingparticipates inPathwayRAS-RAF-MEK-ERK Signaling (MAPK)participates inProteinSOS1recruits
All 4 Structured Connections
GRB2 · GeneENCODES →GRB2 · Protein
GRB2 · ProteinPARTICIPATES IN →Receptor Tyrosine kinase signaling · Pathway
GRB2 · ProteinPARTICIPATES IN →RAS-RAF-MEK-ERK Signaling (MAPK) · Pathway
GRB2 · ProteinRECRUITS →SOS1 · Protein

Recommended Reading

Trusted references for learning more about GRB2.

pathwaySignaling by Receptor Tyrosine Kinases (R-HSA-9006934)Reactome · Homo sapiens pathwayRAF/MAP kinase cascade (R-HSA-5673001)Reactome · Homo sapiens databaseGRB2 (2885)NCBI Gene
Research Claims

An adaptor protein that helps recruit SOS-family exchange factors to activated receptor signaling complexes.