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Protein

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

A RAS guanine-nucleotide exchange factor. When recruited to signaling complexes, SOS1 can promote the active, GTP-bound state of RAS.

Overview

EXPLORE BY LEVEL

SOS1 is a protein that helps pass or control signals inside cells. A RAS guanine-nucleotide exchange factor. When recruited to signaling complexes, SOS1 can promote the active, GTP-bound state of RAS.

Quick Facts

AT A GLANCE
Encoded bySOS1
Rolemapk signaling

Follow the Connections

See how SOS1 links to other biological records.

Open network
GeneSOS1encodesPathwayRAS-RAF-MEK-ERK Signaling (MAPK)participates inProteinGRB2recruitsProteinKRASactivates
All 4 Structured Connections
SOS1 · GeneENCODES →SOS1 · Protein
SOS1 · ProteinPARTICIPATES IN →RAS-RAF-MEK-ERK Signaling (MAPK) · Pathway
GRB2 · ProteinRECRUITS →SOS1 · Protein
SOS1 · ProteinACTIVATES →KRAS · Protein

Recommended Reading

Trusted references for learning more about SOS1.

pathwayRAF/MAP kinase cascade (R-HSA-5673001)Reactome · Homo sapiens databaseSOS1 (6654)NCBI Gene
Research Claims

A RAS guanine-nucleotide exchange factor. When recruited to signaling complexes, SOS1 can promote the active, GTP-bound state of RAS.