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Protein · enzymePROTEIN · ENZYME RECORD

Pyruvate dehydrogenase complex

Mitochondrial multienzyme complex that oxidatively decarboxylates pyruvate to acetyl-CoA.

Pyruvate oxidationHomo sapiens
REFERENCE IDENTIFIER1.2.4.1EC record
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Pyruvate dehydrogenase complex is a protein that speeds up a chemical reaction. Cells can adjust when and how strongly many enzymes work.

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Record type: enzyme. Mitochondrial multienzyme complex that oxidatively decarboxylates pyruvate to acetyl-CoA.
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HUMAN GENESPDHA1Explore gene DLATExplore gene DLDExplore gene
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Connected records

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Catalyzes a step inPyruvate oxidationUsesPyruvateUsesCoenzyme AUsesNAD+ProducesAcetyl-CoAProducesCarbon dioxideProducesNADHProducesProton
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Encoded byPDHA1Encoded byDLATEncoded byDLD
STRUCTURED REACTIONS

Reactions it catalyzes

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Pyruvate dehydrogenase reaction

The multienzyme complex oxidizes pyruvate, releases CO2, and forms acetyl-CoA and NADH.

Pyruvate oxidation · irreversible